BDBM323037 N,1-Dimethyl-4-[({(1R,2R and 1S,2S)-2- [4-(1H-pyrazol-3-yl)benzoyl]cyclohexyl}- carbonyl)amino]-1H-pyrazole-3- carboxamide::US10183947, Example 20::US10508119, Example 20

SMILES CNC(=O)c1nn(C)cc1NC(=O)C1CCCCC1C(=O)c1ccc(cc1)-c1cc[nH]n1

InChI Key InChIKey=DQRHMGIZNFDJFP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 323037   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Astrazeneca

US Patent
LigandPNGBDBM323037(US10183947, Example 20 | N,1-Dimethyl-4-[({(1R,2R ...)
Affinity DataIC50: 180nMAssay Description:Compounds were tested in a competition binding assay using 3H-MK591 as tracer. (Preparation of MK-591 is described in Bioorg. Med. Chem. Lett. 1999, ...More data for this Ligand-Target Pair
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Date in BDB:
5/16/2019
Entry Details
US Patent