BDBM323044 (1R,2R)-N-[5-(Dimethylsulfamoyl)-1- methyl-1H-pyrazol-4-yl]-2-[4-(1H-pyrazol- 5-yl)benzoyl]cyclohexanecarboxamide::US10183947, Example 27::US10508119, Example 27::US11001589, Example 27::US11691978, Example 27

SMILES CN(C)S(=O)(=O)c1c(NC(=O)[C@@H]2CCCC[C@H]2C(=O)c2ccc(cc2)-c2ccn[nH]2)cnn1C

InChI Key InChIKey=SLKIJLWTLRMCBG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 323044   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Astrazeneca

US Patent
LigandPNGBDBM323044(US10183947, Example 27 | (1R,2R)-N-[5-(Dimethylsul...)
Affinity DataIC50: 65nMAssay Description:Compounds were tested in a competition binding assay using 3H-MK591 as tracer. (Preparation of MK-591 is described in Bioorg. Med. Chem. Lett. 1999, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent