BDBM323045 (1R,2R)-N-(2-Methyl-4-oxo-4,5,6,7- tetrahydropyrazolo[1,5-a]pyrazin-3-yl)-2- [4-(5-methyl-1H-pyrazol-3- yl)benzoyl]cyclohexanecarboxamide::US10183947, Example 28::US10508119, Example 28::US11001589, Example 28::US11691978, Example 28

SMILES Cc1cc(-c2ccc(C(=O)[C@@H]3CCCC[C@H]3C(=O)Nc3c(C)nn4c3C(=O)NCC4)cc2)n[nH]1

InChI Key InChIKey=YRMFEJNGSRRDCN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 323045   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
AstraZeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 323045BDBM323045(US10183947, Example 28 | (1R,2R)-N-(2-Methyl-4-oxo...)
Affinity DataIC50: 3.90nMAssay Description:Compounds were tested in a competition binding assay using 3H-MK591 as tracer. (Preparation of MK-591 is described in Bioorg. Med. Chem. Lett. 1999, ...More data for this Ligand-Target Pair
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Date in BDB:
5/16/2019
Entry Details
US Patent