BDBM323047 (1R,2R)-N-[5-(Difluoromethyl)-1H- pyrazol-4-yl]-2-[4-(1H-pyrazol-3- yl)benzoyl]cyclohexanecarboxamide::US10183947, Example 30::US10508119, Example 30::US11001589, Example 30::US11691978, Example 30

SMILES FC(F)c1[nH]ncc1NC(=O)[C@@H]1CCCC[C@H]1C(=O)c1ccc(cc1)-c1cc[nH]n1

InChI Key InChIKey=FHGRHSAUCVRESR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 323047   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Astrazeneca

US Patent
LigandPNGBDBM323047(US10183947, Example 30 | (1R,2R)-N-[5-(Difluoromet...)
Affinity DataIC50: 12nMAssay Description:Compounds were tested in a competition binding assay using 3H-MK591 as tracer. (Preparation of MK-591 is described in Bioorg. Med. Chem. Lett. 1999, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent