BDBM323051 4-[({(1R,2R or 1S,2S)-2-[2-Fluoro-4-(1H- pyrazol-5-yl)benzoyl] cyclohexyl}carbonyl)amino]-1-methyl-1H- pyrazole-5-carboxamide::US10183947, Example 34::US10508119, Example 34

SMILES Cn1ncc(NC(=O)C2CCCCC2C(=O)c2ccc(cc2F)-c2ccn[nH]2)c1C(N)=O

InChI Key InChIKey=RLVGSZOMIOBSAN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 323051   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Astrazeneca

US Patent
LigandPNGBDBM323051(US10183947, Example 34 | 4-[({(1R,2R or 1S,2S)-2-[...)
Affinity DataIC50: 41nMAssay Description:Compounds were tested in a competition binding assay using 3H-MK591 as tracer. (Preparation of MK-591 is described in Bioorg. Med. Chem. Lett. 1999, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent