BDBM323060 (1R,2R)-2-[4-(3-Methyl-1H-pyrazol-5- yl)benzoyl]-N-(1,3,4-oxadiazol-2- yl)cyclohexanecarboxamide::US10183947, Example 43::US10508119, Example 43::US11001589, Example 43::US11691978, Example 43

SMILES Cc1cc(-c2ccc(C(=O)[C@@H]3CCCC[C@H]3C(=O)Nc3nnco3)cc2)[nH]n1

InChI Key InChIKey=HWRHVHFUHOPJNJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 323060   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
AstraZeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 323060BDBM323060(US10183947, Example 43 | (1R,2R)-2-[4-(3-Methyl-1H...)
Affinity DataIC50: 140nMAssay Description:Compounds were tested in a competition binding assay using 3H-MK591 as tracer. (Preparation of MK-591 is described in Bioorg. Med. Chem. Lett. 1999, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent