BDBM323062 (1R,2R and 1S,2S)-N-(4-Methyl-1,3- oxazol-2-yl)-2-[4-(1H-pyrazol-5- yl)benzoyl]cyclohexanecarboxamide::US10183947, Example 45::US10508119, Example 45

SMILES Cc1coc(NC(=O)C2CCCCC2C(=O)c2ccc(cc2)-c2ccn[nH]2)n1

InChI Key InChIKey=NIGCKTGKYXUAQP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 323062   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Astrazeneca

US Patent
LigandPNGBDBM323062(US10183947, Example 45 | (1R,2R and 1S,2S)-N-(4-Me...)
Affinity DataIC50: 210nMAssay Description:Compounds were tested in a competition binding assay using 3H-MK591 as tracer. (Preparation of MK-591 is described in Bioorg. Med. Chem. Lett. 1999, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent