BDBM323494 (1S,2R)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Propane-1,2-Diol::US10188615, Example 180::US10639286, Example 180

SMILES NC[C@@H](O)[C@@H](O)c1cccc(OCC2CCCCC2)c1

InChI Key InChIKey=SOEYVCWIGWTSCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323494   

TargetRetinaldehyde-binding protein 1(Human)
Acucela

US Patent
LigandPNGBDBM323494((1S,2R)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Pro...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J Biol. Chem. 274:8577-85 (1999).More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandPNGBDBM323494((1S,2R)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Pro...)
Affinity DataIC50: 55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent