BDBM324174 US10189819, Example 3

SMILES Cc1cc2nc(C(CNC(=O)c3ccc(-n4cc(CCO)nn4)cc3Cl)c3ccccc3)[nH]c2cc1C

InChI Key InChIKey=MVAICMRNSARGFO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 324174   

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 324174BDBM324174(US10189819, Example 3)
Affinity DataIC50: 21.9nMAssay Description:Formation of a clot to stem bleeding at a site of blood vessel injury involves the coordinated activity of a group of plasma proteins that initiate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent