BDBM324179 US10189819, Example 8

SMILES Cc1ncn(-c2cc(C)c(C(=O)NCC(c3ccccc3)c3nc4cc(C)c(C)cc4[nH]3)c(Cl)c2)n1

InChI Key InChIKey=HSKKWLQBYHXRTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 324179   

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 324179BDBM324179(US10189819, Example 8)
Affinity DataIC50: 6.99nMAssay Description:Formation of a clot to stem bleeding at a site of blood vessel injury involves the coordinated activity of a group of plasma proteins that initiate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent