BDBM324221 US10189819, Example 58

SMILES COc1cc2nc([C@@H](CNC(=O)c3c(Cl)cc(-n4cnc(C)n4)cc3Cl)c3ccc(C(N)=O)cc3)[nH]c2cc1Cl

InChI Key InChIKey=ROWVFJBEDJHJAB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 324221   

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 324221BDBM324221(US10189819, Example 58)
Affinity DataIC50: 2.36nMAssay Description:Formation of a clot to stem bleeding at a site of blood vessel injury involves the coordinated activity of a group of plasma proteins that initiate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent