BDBM324339 N-(2-(2-((1H-pyrazol-4- yl)amino)pyrimidin-4- yl)-6,7,8,9-tetrahydro- 5H-benzo[7]annulen-5- yl)-5-(tert-butyl)-1,3,4- oxadiazole-2- carboxamide::US10189829, Compound 114::US10227341, Compound 114::US10961237, Compound 114::US11858926, Compound 114

SMILES CC(C)(C)c1nnc(o1)C(=O)NC1CCCCc2cc(ccc12)-c1ccnc(Nc2cn[nH]c2)n1

InChI Key InChIKey=VZMOTJGQAHZISN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 324339   

TargetTyrosine-protein kinase BTK [14-552](Human)
Biogen Ma

US Patent
LigandPNGBDBM324339(N-(2-(2-((1H-pyrazol-4- yl)amino)pyrimidin-4- yl)-...)
Affinity DataIC50: 1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Biogen Ma

US Patent
LigandPNGBDBM324339(N-(2-(2-((1H-pyrazol-4- yl)amino)pyrimidin-4- yl)-...)
Affinity DataIC50: 1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Biogen Ma

US Patent
LigandPNGBDBM324339(N-(2-(2-((1H-pyrazol-4- yl)amino)pyrimidin-4- yl)-...)
Affinity DataIC50: 1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Biogen Ma

US Patent
LigandPNGBDBM324339(N-(2-(2-((1H-pyrazol-4- yl)amino)pyrimidin-4- yl)-...)
Affinity DataIC50: 505nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent