BDBM324515 1-(4-methylpiperazin-1- yl)-2-[4-[[8-[(1S,5R)-8-(3- pyridylmethoxy)-3- azabicyclo[3.2.1]octan-3- yl]-[1,2,4]triazolo[1,5-a] pyridin-2-yl]amino]pyrazol- 1-yl]ethanone::US10189836, Example 84
SMILES CN1CCN(CC1)C(=O)Cn1cc(Nc2nc3c(cccn3n2)N2C[C@@H]3CC[C@H](C2)[C@@H]3OCc2cccnc2)cn1
InChI Key InChIKey=DVMPOQZRASMZNY-OOWSSMPZSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 324515
Affinity DataKi: 0.400nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair