BDBM324827 2-(2-cyclopropylpyridin-3-yl)-::US10189841, Compound I-33::US10399980, Compound I-33

SMILES FC(F)(F)c1cn(C2COC2)c(n1)-c1ccc(Cn2c3nc(ncc3[nH]c2=O)-c2cccnc2C2CC2)cc1

InChI Key InChIKey=LSNJOUYKHUSCTD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 324827   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM324827(2-(2-cyclopropylpyridin-3-yl)- | US10189841, Compo...)
Affinity DataIC50: 50nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM324827(2-(2-cyclopropylpyridin-3-yl)- | US10189841, Compo...)
Affinity DataIC50: 50nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent