BDBM325079 2-(2-isopropylphenyl)-7-methyl-9-(4-(1-methyl-1H-::US10189841, Compound I-285::US10189841, Compound I-298::US10399980, Compound I-285::US11161848, Compound I-285

SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-c3cnnn3C)c2n1

InChI Key InChIKey=KEYQNLYNEOYIKI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 325079   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM325079(2-(2-isopropylphenyl)-7-methyl-9-(4-(1-methyl-1H- ...)
Affinity DataIC50: <200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM325079(2-(2-isopropylphenyl)-7-methyl-9-(4-(1-methyl-1H- ...)
Affinity DataIC50:  1.10E+3nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM325079(2-(2-isopropylphenyl)-7-methyl-9-(4-(1-methyl-1H- ...)
Affinity DataIC50:  1.10E+3nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM325079(2-(2-isopropylphenyl)-7-methyl-9-(4-(1-methyl-1H- ...)
Affinity DataIC50: <0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent