BDBM325329 US10189841, Compound I-535::US10399980, Compound I-535

SMILES COc1nc(nc2n(Cc3ccc(cc3)-c3nc(cn3C)C(F)(F)F)c(=O)[nH]c12)-c1ccccc1C(C)C

InChI Key InChIKey=XTBSNKAGWPDDCV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 325329   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM325329(US10189841, Compound I-535 | US10399980, Compound ...)
Affinity DataIC50: 50nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM325329(US10189841, Compound I-535 | US10399980, Compound ...)
Affinity DataIC50: 50nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent