BDBM325727 4-(2,6-dichloro-4-fluorophenyl)quinoline-2-carboxamide::US9636337, 1-9

SMILES NC(=O)c1cc(-c2c(Cl)cc(F)cc2Cl)c2ccccc2n1

InChI Key InChIKey=WKRWMZGTVCYGBC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 325727   

TargetMetabotropic glutamate receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 325727BDBM325727(4-(2,6-dichloro-4-fluorophenyl)quinoline-2-carboxa...)
Affinity DataIC50: 171nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent