BDBM325761 (rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[c]pyridin-7-yl]-N-(1H-pyrazol-3-yl)acetamide::US9636339, 11

SMILES O=C(CC1CCc2c(-c3ccc(C(F)(F)F)c(F)c3)cncc21)Nc1cc[nH]n1

InChI Key InChIKey=XOCSBMJANWUYCX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 325761   

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325761BDBM325761((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  8nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325761BDBM325761((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  30nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent