BDBM326251 3-(1-(9H-purin-6-yl)pyrrolidin-2-yl)-7-fluoro-2-(pyridin-3-yl)quinoline ::US9637488, 1

SMILES Fc1ccc2cc(C3CCCN3c3ncnc4[nH]cnc34)c(nc2c1)-c1cccnc1

InChI Key InChIKey=PELZJDNCZDWFNG-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 326251   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
TBA

US Patent

LigandBDBM326251(3-(1-(9H-purin-6-yl)pyrrolidin-2-yl)-7-fluoro-2-(p...)Copy SMILESCopy InChI

Affinity DataIC50: 27nMAssay Description:Exemplary compounds of the invention were tested their inhibitory activity or potency against PI3Kδ in 10-dose IC50 mode with 3-fold serial dilu...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/29/2019
Entry Details
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