BDBM326252 4-amino-6-(2-(7-fluoro-2-morpholinoquinolin-3-yl)pyrrolidin-1-yl)pyrimidine-5-carbonitrile::US9637488, 7

SMILES Nc1ncnc(N2CCCC2c2cc3ccc(F)cc3nc2N2CCOCC2)c1C#N

InChI Key InChIKey=CNNVISSMGRRJFB-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 326252   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
TBA

US Patent

LigandBDBM326252(4-amino-6-(2-(7-fluoro-2-morpholinoquinolin-3-yl)p...)Copy SMILESCopy InChI

Affinity DataIC50: 1.60nMAssay Description:Exemplary compounds of the invention were tested their inhibitory activity or potency against PI3Kδ in 10-dose IC50 mode with 3-fold serial dilu...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/29/2019
Entry Details
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