BDBM326253 3-(1-(9H-purin-6-yl)pyrrolidin-2-yl)-7-fluoro-2-(pyridin-2-yl)quinoline::US9637488, 10::US9637488, 14

SMILES Fc1ccc2cc(C3CCCN3c3ncnc4[nH]cnc34)c(nc2c1)-c1ccccn1

InChI Key InChIKey=DWGPQDAXSIFCLM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 326253   

LigandPNGBDBM326253(US9637488, 10 | 3-(1-(9H-purin-6-yl)pyrrolidin-2-y...)
Affinity DataIC50: 13nMAssay Description:Exemplary compounds of the invention were tested their inhibitory activity or potency against PI3Kδ in 10-dose IC50 mode with 3-fold serial dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM326253(US9637488, 10 | 3-(1-(9H-purin-6-yl)pyrrolidin-2-y...)
Affinity DataIC50: 521nMAssay Description:Exemplary compounds of the invention were tested their inhibitory activity or potency against PI3Kδ in 10-dose IC50 mode with 3-fold serial dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent