BDBM326988 N-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyridin-3-yl]benzyl}-N-methyl- 2-(pyridin-2-yl)ethanamine::US11957671, Compound 138::US9662339, 138

SMILES CN(CCc1ccccn1)Cc1ccc(cc1)[C@H]1COc2cccnc2O1

InChI Key InChIKey=VDSZUUVUSUWIDX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 326988   

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandPNGBDBM326988(N-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyrid...)
Affinity DataIC50: 0.180nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandPNGBDBM326988(N-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyrid...)
Affinity DataIC50: 0.180nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
US Patent