BDBM327059 1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benzyl}-N-(2- hydroxyethyl)piperidine-4- carboxamide::US11957671, Compound 96::US9662339, 96

SMILES OCCNC(=O)C1CCN(Cc2ccc(cc2)[C@H]2COc3ccccc3O2)CC1

InChI Key InChIKey=VHULLKJQDATRQJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327059   

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandPNGBDBM327059(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benz...)
Affinity DataIC50: 0.220nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandPNGBDBM327059(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2-yl]benz...)
Affinity DataIC50: 0.220nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
US Patent