BDBM327136 1-(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- yl]benzyl}piperidin-4-yl)urea::US11957671, Compound 175::US9662339, 175

SMILES NC(=O)NC1CCN(Cc2ccc(cc2)[C@H]2COc3ccccc3O2)CC1

InChI Key InChIKey=HUIQHYCNINCSRR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327136   

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM327136(1-(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- yl...)
Affinity DataIC50: 0.220nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM327136(1-(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- yl...)
Affinity DataIC50: 0.220nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent