BDBM327466 1-[4-amino-5-chloro-2-(2-fluoroéthoxy)phenyl]-3-[1-(cyclohexylmethyl)-4-piperidyl]propan-1-one::US9663465, 23

SMILES Nc1cc(OCCF)c(cc1Cl)C(=O)CCC1CCN(CC2CCCCC2)CC1

InChI Key InChIKey=RYDDBILRWHKYGG-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327466   

Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Universite De Caen

US Patent
LigandPNGBDBM327466(1-[4-amino-5-chloro-2-(2-fluoroéthoxy)phenyl]-3-[1...)
Affinity DataKi:  2.5nMAssay Description:Prior to these competition studies, a series of saturation curves were performed in order to check whether the pharmacological parameters Kd, Bmax an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetylcholinesterase(Homo sapiens (Human))
Universite De Caen

US Patent
LigandPNGBDBM327466(1-[4-amino-5-chloro-2-(2-fluoroéthoxy)phenyl]-3-[1...)
Affinity DataIC50:  625nMAssay Description:Acetylcholinesterase extracted from human erythrocytes (buffered aqueous solution, ≧500 units/mg, Sigma Aldrich) is diluted in a 20 mM HEPES bu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent