BDBM327780 (1H-Benzoimidazol-5-yl)-[(4a-S,10b-R)-2,3, 4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-4-yl]-methanone::US9663470, 2

SMILES O=C(c1ccc2[nH]cnc2c1)N1CCC[C@@H]2c3ccccc3CC[C@@H]21

InChI Key InChIKey=LDXJDJWFSSSGPR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327780   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 327780BDBM327780((1H-Benzoimidazol-5-yl)-[(4a-S,10b-R)-2,3, 4a,5,6,...)
Affinity DataIC50: 65nMAssay Description:In vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent