BDBM327859 6-tert-butyl-8-fluoro- 2-[2-methyl-3-[1- methyl-5-[[5- (morpholine-4- carbonyl)pyridin-2- yl]amino]-6- oxopyridazin-3- yl]phenyl]phthalazin- 1-one::US9663494, Compound 7

SMILES Cc1c(cccc1-n1ncc2cc(cc(F)c2c1=O)C(C)(C)C)-c1cc(Nc2ccc(cn2)C(=O)N2CCOCC2)c(=O)n(C)n1

InChI Key InChIKey=XXOIRJODGNBWBK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327859   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM327859(6-tert-butyl-8-fluoro- 2-[2-methyl-3-[1- methyl-5-...)
Affinity DataIC50: 6.5nMAssay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of BTK, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent