BDBM328336 6-(4-(4- fluorophenylsulfonyl) piperidine-1-carbonyl)- N-(1-(4-methoxybenzyl) piperidin-4- yl)nicotinamide::US10377742, Compound 474::US9663496, Compound 474

SMILES COc1ccc(CN2CCC(CC2)NC(=O)c2ccc(nc2)C(=O)N2CCC(CC2)S(=O)(=O)c2ccc(F)cc2)cc1

InChI Key InChIKey=JRJGDHLBBROFNB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328336   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 328336BDBM328336(US9663496, Compound 474 | 6-(4-(4- fluorophenylsul...)
Affinity DataEC50:  3.00E+3nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 328336BDBM328336(US9663496, Compound 474 | 6-(4-(4- fluorophenylsul...)
Affinity DataEC50:  3.00E+3nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent