BDBM328341 N-(6-(4-cyanophenoxy)- 2-methylpyridin-3-yl)-6- (4-(2,4-difluorobenzoyl) piperidine-1- carbonyl)nicotinamide::US10377742, Compound 479::US9663496, Compound 479

SMILES Cc1nc(Oc2ccc(cc2)C#N)ccc1NC(=O)c1ccc(nc1)C(=O)N1CCC(CC1)C(=O)c1ccc(F)cc1F

InChI Key InChIKey=FGKOOCQTYBWAPY-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328341   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328341(US9663496, Compound 479 | N-(6-(4-cyanophenoxy)- 2...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328341(US9663496, Compound 479 | N-(6-(4-cyanophenoxy)- 2...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent