BDBM330051 (1S,4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-6,8-dioxo-1,2,3,4,6,8,12,12a-octahydro-1,4-methanodipyrido[1,2-a:1′,2′-d]pyrazine-9-carboxamide::US10689399, Compound 48::US9663528, 48

SMILES O=C(NCc1ccc(F)cc1F)c1cn2c(c(O)c1=O)C(=O)N1[C@@H]3CC[C@@H](C3)[C@H]1C2

InChI Key InChIKey=WKGDGYMWVQYBAY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330051   

TargetPOU domain, class 2, transcription factor 2(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 330051BDBM330051(US9663528, 48 | (1S,4R,12aS)-N-(2,4-difluorobenzyl...)
Affinity DataIC50: 4.91E+3nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetSolute carrier family 22 member 2(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 330051BDBM330051(US9663528, 48 | (1S,4R,12aS)-N-(2,4-difluorobenzyl...)
Affinity DataIC50: 4.91E+3nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent