BDBM330064 (S)-2-amino-N-(5H- chromeno[3,4- c]pyridin-8-yl)-4- phenylbutanamide::US9663529, Example I-3

SMILES N[C@@H](CCc1ccccc1)C(=O)Nc1ccc-2c(OCc3cnccc-23)c1

InChI Key InChIKey=YNMRRKYGGSQSFU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 330064   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM330064(US9663529, Example I-3 | (S)-2-amino-N-(5H- chrome...)
Affinity DataIC50: 284nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent