BDBM330131 N-(5H-chromeno[3,4- c]pyridin-8-yl)-2-(4- (4-oxoquinazolin- 3(4H)-yl)phenyl) acetamide::US9663529, Example I-70

SMILES O=C(Cc1ccc(cc1)-n1cnc2ccccc2c1=O)Nc1ccc-2c(OCc3cnccc-23)c1

InChI Key InChIKey=QUOZICDGQPLCLE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 330131   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 330131BDBM330131(US9663529, Example I-70 | N-(5H-chromeno[3,4- c]py...)
Affinity DataIC50: 1.13E+3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent