BDBM330157 2-(3-Cyanophenyl)-N-(9H-pyrido[3,4-b]indol-7-yl)acetamide::US9663529, Example IV-5

SMILES O=C(Cc1cccc(c1)C#N)Nc1ccc2c(c1)[nH]c1cnccc21

InChI Key InChIKey=HLJFZORHOKHYCJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 330157   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM330157(US9663529, Example IV-5 | 2-(3-Cyanophenyl)-N-(9H-...)
Affinity DataIC50: 383nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent