BDBM330439 US9725442, Compound I-62::US9725442, Compound I-63

SMILES CC(C)Oc1ccc(cc1)S(=O)(=O)N1C[C@@H](C)[C@H](C1)n1nc(CC(O)=O)c2ccc(C)cc12

InChI Key InChIKey=PYXYKPRIPPTACH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 330439   

TargetProstaglandin D2 receptor 2(Human)
Shionogi

US Patent
LigandPNGBDBM330439(US9725442, Compound I-62 | US9725442, Compound I-6...)
Affinity DataKi:  3.10nMAssay Description:Cell membrane was prepared from CRTH2-expressing K562 cell. The cell membrane (20 μg/well) was mixed with reaction buffer (50 mM Tris/HCl, pH 7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
Shionogi

US Patent
LigandPNGBDBM330439(US9725442, Compound I-62 | US9725442, Compound I-6...)
Affinity DataKi: <100nMAssay Description:Cell membrane was prepared from CRTH2-expressing K562 cell. The cell membrane (20 μg/well) was mixed with reaction buffer (50 mM Tris/HCl, pH 7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
Shionogi

US Patent
LigandPNGBDBM330439(US9725442, Compound I-62 | US9725442, Compound I-6...)
Affinity DataKi: <100nMAssay Description:Cell membrane was prepared from CRTH2-expressing K562 cell. The cell membrane (20 μg/well) was mixed with reaction buffer (50 mM Tris/HCl, pH 7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent