BDBM332016 (R)- or (S)-6''- (1-(4-(difluoro- methyl)-3- fluoro- phenyl)ethyl)- 2-methyl- [4,4''- bipyrimidin]- 6(1H)-one::US10195201, Example 38::US10195201, Example 39

SMILES CC(c1ccc(C(F)F)c(F)c1)c1cc(ncn1)-c1cc(=O)[nH]c(C)n1

InChI Key InChIKey=IVBTYOQKPWSULH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 332016   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM332016(US10195201, Example 39 | (R)- or (S)-6''- (1-(4-(d...)
Affinity DataKi:  30nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM332016(US10195201, Example 39 | (R)- or (S)-6''- (1-(4-(d...)
Affinity DataKi:  174nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent