BDBM332310 US10189854, Compound 274

SMILES O=C(N1CC2CC1CN2)c1ccc2c(c1)N(CC21CC1)c1ncc(cn1)-c1cccnn1

InChI Key InChIKey=XQFVVSKNCUIUFE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332310   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332310(US10189854, Compound 274)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent