BDBM332330 US10189854, Compound 294

SMILES CC(C)(O)c1ccnc(c1)-c1cnc(nc1)N1CC2(CC2)c2ccc(cc12)C(=O)N1CCOCC1

InChI Key InChIKey=TTZVGWCMQPLOFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332330   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332330(US10189854, Compound 294)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent