BDBM332580 (2E)-1-{2-[(2E)-3-(3,4-dichlorophenyl)prop-2-enoyl]-2,7-diazaspiro[3.5]non-7-yl}-3-(3,4-dichlorophenyl)prop-2-en-1-one::US10196369, Compound C35

SMILES Clc1ccc(\C=C\C(=O)N2CC3(C2)CCN(CC3)C(=O)\C=C\c2ccc(Cl)c(Cl)c2)cc1Cl

InChI Key InChIKey=YWMLTXBSPOLXIK-FCXRPNKRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332580   

TargetG-protein coupled receptor 183(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM332580((2E)-1-{2-[(2E)-3-(3,4-dichlorophenyl)prop-2-enoyl...)
Affinity DataIC50: <5nMAssay Description:The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent