BDBM332679 US10196374, Example 7

SMILES CC(C)[C@H](NC(=O)C(C)(F)F)[C@H](Oc1ccc2n(ncc2c1)-c1ccc(=O)n(C)c1)c1ccc(Cl)cc1

InChI Key InChIKey=YPEHYXYBPJHXEV-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 332679   

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM332679(US10196374, Example 7)
Affinity DataEC50:  7.94nMAssay Description:A reporter cell line (ChagoK1 18:7:2 s4/GRE) was established by stable transfection of the human bronchogenic carcinoma cell line, ChaGo K1 (ATCC: HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM332679(US10196374, Example 7)
Affinity DataIC50: 79.4nMAssay Description:A reporter cell line (ChagoK1 18:7:2 s4/GRE) was established by stable transfection of the human bronchogenic carcinoma celline, ChaGo K1 (ATCC: HTB ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent