BDBM332706 US10196378, Compound C09::US10196378, Compound C10
SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccc4cccnc4c3)cc2)n(n1)-c1ccc2ncccc2c1
InChI Key InChIKey=DQLDULIEUKHCJI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 332706
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: 0.640nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1 [Y253F](Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: 2.5nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: 3.30nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1 [Y253F](Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: 7.60nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: 143nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: 345nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataIC50: 719nMAssay Description:Inhibition of NanoLuc-tagged ABL1 wild type (unknown origin) expressed in HEK293 cells by NanoBRET TE assayMore data for this Ligand-Target Pair