BDBM332730 6-fluoro-2-(4-(5-trifluoromethylpyridin-2-yl)piperazin-1-yl)-1H-benzimidazole-4-carboxamide::US10196381, Compound (21)

SMILES NC(=O)c1cc(F)cc2[nH]c(nc12)N1CCN(CC1)c1ccc(cn1)C(F)(F)F

InChI Key InChIKey=GDPVLLLJNTVSBC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332730   

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332730(US10196381, Compound (21) | 6-fluoro-2-(4-(5-trifl...)
Affinity DataIC50: 68nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent