BDBM332750 2-(4-(2-ethylcarbamoylpyrimidin-5-yl)piperazin-1-yl)-6-fluoro-1H-benzimidazole-4-carboxamide::US10196381, Compound (40)

SMILES CCNC(=O)c1ncc(cn1)N1CCN(CC1)c1nc2c(cc(F)cc2[nH]1)C(N)=O

InChI Key InChIKey=YHCBNJLNFOKXHJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332750   

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Huilun Life Science & Technology

US Patent
LigandPNGBDBM332750(US10196381, Compound (40) | 2-(4-(2-ethylcarbamoyl...)
Affinity DataIC50: 9nMAssay Description:1. 50 μl of 1×PARP buffer per well was added to infiltrate the histone, and the plate was incubated for 30 min at room temperature. Then the 1×P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent