BDBM333116 6-(2-chloro-6-methoxy-4-pyridyl)-2-pyrimidin-2-yl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine::US10196391, Example 116

SMILES COc1cc(cc(Cl)n1)N1CCc2nc(ncc2C1)-c1ncccn1

InChI Key InChIKey=SAHYVKVIXQENOL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333116   

TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333116(US10196391, Example 116 | 6-(2-chloro-6-methoxy-4-...)
Affinity DataIC50: 530nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2019
Entry Details
US Patent