BDBM333171 US10196436, Compound 22

SMILES Cc1cccc(NC(=O)C=C)c1Nc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1

InChI Key InChIKey=HPBSSUWBGJFMQS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 333171   

TargetFibroblast growth factor receptor 4(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM333171(US10196436, Compound 22)
Affinity DataIC50: 55nMAssay Description:In each well of a 384-well plate, 0.5 ng/ul of wild type FGFR-4 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM333171(US10196436, Compound 22)
Affinity DataIC50: 1.00E+3nMAssay Description:In each well of a 384-well plate, 0.1 ng/ul of wild type FGFR-1 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2019
Entry Details
US Patent