BDBM333194 US10196436, Compound 44

SMILES COc1cc(OC)cc(c1)-c1cc2cnc(Nc3ccccc3NC(=O)C=C)cc2nc1NC(=O)NC(C)(C)C

InChI Key InChIKey=UKXDPISBDDJLJF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 333194   

TargetFibroblast growth factor receptor 4(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM333194(US10196436, Compound 44)
Affinity DataIC50: 550nMAssay Description:In each well of a 384-well plate, 0.5 ng/ul of wild type FGFR-4 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM333194(US10196436, Compound 44)
Affinity DataIC50: 1.00E+3nMAssay Description:In each well of a 384-well plate, 0.1 ng/ul of wild type FGFR-1 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2019
Entry Details
US Patent