BDBM333195 US10196436, Compound 45

SMILES C=CC(=O)Nc1cccc(C)c1Nc1ncc2nc(-c3c(Cl)c(OC)cc(OC)c3Cl)c(=O)n(C)c2n1

InChI Key InChIKey=KXMWLVDRBYMSHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 333195   

TargetFibroblast growth factor receptor 4(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 333195BDBM333195(US10196436, Compound 45)
Affinity DataIC50: 10nMAssay Description:In each well of a 384-well plate, 0.5 ng/ul of wild type FGFR-4 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 333195BDBM333195(US10196436, Compound 45)
Affinity DataIC50: 1.00E+3nMAssay Description:In each well of a 384-well plate, 0.1 ng/ul of wild type FGFR-1 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2019
Entry Details
US Patent