BDBM334000 (1R,2R)-2-{[(3S)-3-{[9-ethyl-8- (2-methylpyrimidin-5-yl)-9H- purin-6-yl]oxy}pyrrolidin-1- yl]carbonyl}cyclopentanamine::US9730940, Compound 2-101

SMILES CCn1c(nc2c(O[C@H]3CCN(C3)C(=O)[C@@H]3CCC[C@H]3N)ncnc12)-c1cnc(C)nc1

InChI Key InChIKey=OTYFUFVMASKSGG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 334000   

LigandChemical structure of BindingDB Monomer ID 334000BDBM334000((1R,2R)-2-{[(3S)-3-{[9-ethyl-8- (2-methylpyrimidin...)
Affinity DataIC50: 39nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair
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Date in BDB:
6/23/2019
Entry Details
US Patent