BDBM334297 US9732061, Compound 19

SMILES OC(=O)c1ccccc1S(=O)(=O)N1CCC(CC1)Nc1cnnc2ccc(cc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key InChIKey=ITZSQLJPQWMJBB-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 334297   

TargetCannabinoid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM334297(US9732061, Compound 19)
Affinity DataEC50:  5.94E+3nMAssay Description:The following mixtures and buffer solutions were prepared: (a) Buffer 1: HBSS (Mediatech Cat#21-023-CV) with 5 mM HEPES (1 mM stock, Gibco BRL Cat#15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetCannabinoid receptor 2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM334297(US9732061, Compound 19)
Affinity DataEC50: >1.00E+4nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in HEK293 cells assessed as forskolin-stimulated cAMP accumulation measured after 30 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM334297(US9732061, Compound 19)
Affinity DataEC50:  5.94E+3nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in HEK293 cells assessed as forskolin-stimulated cAMP accumulation measured after 30 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM334297(US9732061, Compound 19)
Affinity DataEC50: >1.00E+4nMAssay Description:The following mixtures and buffer solutions were prepared: (a) Buffer 1: HBSS (Mediatech Cat#21-023-CV) with 5 mM HEPES (1 mM stock, Gibco BRL Cat#15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent