BDBM33514 2-(2-bromophenyl)-5-[(5-methyl-2-furanyl)methylidene]-6-thiazolo[3,2-b][1,2,4]triazolone::2-(2-bromophenyl)-5-[(5-methyl-2-furyl)methylene]thiazolo[3,2-b][1,2,4]triazol-6-one::2-(2-bromophenyl)-5-[(5-methylfuran-2-yl)methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one::MLS000039533::SMR000034950::cid_662189

SMILES Cc1ccc(C=c2sc3nc(nn3c2=O)-c2ccccc2Br)o1

InChI Key InChIKey=BVUAQJINEZJNCE-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 33514   

TargetProthrombin(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33514(2-(2-bromophenyl)-5-[(5-methyl-2-furanyl)methylide...)
Affinity DataIC50: >5.00E+4nMpH: 7.5 T: 2°CAssay Description:HTS was performed using 217,350 compounds of the MLSCN library individually plated into 10ul 1536 compound plates at a concentration of 2.5 mM each, ...More data for this Ligand-Target Pair
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TargetHuntingtin(Homo sapiens (Human))
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33514(2-(2-bromophenyl)-5-[(5-methyl-2-furanyl)methylide...)
Affinity DataIC50: >8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM33514(2-(2-bromophenyl)-5-[(5-methyl-2-furanyl)methylide...)
Affinity DataIC50:  3.18E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
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TargetCarboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM33514(2-(2-bromophenyl)-5-[(5-methyl-2-furanyl)methylide...)
Affinity DataIC50:  5.95E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
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TargetEstrogen receptor beta(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM33514(2-(2-bromophenyl)-5-[(5-methyl-2-furanyl)methylide...)
Affinity DataIC50:  5.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...More data for this Ligand-Target Pair
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TargetM17 leucyl aminopeptidase(Plasmodium falciparum 3D7)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33514(2-(2-bromophenyl)-5-[(5-methyl-2-furanyl)methylide...)
Affinity DataIC50:  9.55E+4nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening...More data for this Ligand-Target Pair
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TargetEstrogen receptor beta(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM33514(2-(2-bromophenyl)-5-[(5-methyl-2-furanyl)methylide...)
Affinity DataIC50:  61.1nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay