BDBM335534 (2S,2'S)-isopropyl 2,2'- (((3-acetyl-1-(2-((2S,4R)- 2-(3-chloro-2- fluorobenzylcarbamoyl)- 4-fluoropyrrolidin-1-yl)-2- oxoethyl)-1H-indol-6- yloxy)methyl)phosph- oryl)bis(azanediyl)di- propanoate::US10550140, Compound 24::US9732104, Compound 24

SMILES CC(C)OC(=O)[C@H](C)NP(=O)(COc1ccc2c(cn(CC(=O)N3C[C@H](F)C[C@H]3C(=O)NCc3cccc(Cl)c3F)c2c1)C(C)=O)N[C@@H](C)C(=O)OC(C)C

InChI Key InChIKey=HVQKIGGHZHEMET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 335534   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM335534(US9732104, Compound 24 | (2S,2'S)-isopropyl 2,2'- ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2019
Entry Details
US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM335534(US9732104, Compound 24 | (2S,2'S)-isopropyl 2,2'- ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent